We need your help now

Support from readers like you keeps The Journal open.

You are visiting us because we have something you value. Independent, unbiased news that tells the truth. Advertising revenue goes some way to support our mission, but this year it has not been enough.

If you've seen value in our reporting, please contribute what you can, so we can continue to produce accurate and meaningful journalism. For everyone who needs it.

File photo. Shutterstock/antoniodiaz
Stem Cells

NUIG scientists develop new method of fighting breast cancer

Breast cancer patients whose cancer has spread still face relatively poor outcomes.

A RESEARCH TEAM from NUI Galway has discovered a new method of tackling breast cancer that has spread to other parts of the body.

The scientists from the universities’ Lambe institute spent five years developing the method which exploits a specific type of stem cell and uses it to deliver cancer fighting drugs.

Despite advancements in recent years patients whose breast cancer has spread to other organs still face a relatively poor outcome.

The breakthrough came by investigating how stem cell secretions could be used as a delivery vehicle for medicine.

EV image NUI Galway NUI Galway

The stem cells, which are called Mesenchymal stem cells, can then be used to deliver cancer fighting drugs directly to tumour sites.

The team discovered that tiny vesicles, which are secreted by the adult stem cells, have a remarkable ability to home in on the sites of tumours.

“When cancer has spread it is difficult to deliver therapy to many sites of disease while protecting healthy tissue,” lead author of the study, Dr Róisín Dwyer explained.

However, adult Mesenchymal stem cells have the natural ability to home to the sites of tumours.

The team engineered the cells to fight the growth of tumours and took advantage of its homing ability to develop it into a delivery vehicle for medicine.

The exciting results suggest that the method could be a safe and effective way to treat breast cancer when it has spread to other organs.

The scientists also isolated the vesicles to determine if they could be used to treat the cancer, without the cells. This could also potentially reduce side effects of the treatment.

The research was funded by the Irish Cancer Society’s Breast-Predict centre and the results of the study have been published in the journal Oncogene.

READ: People living in areas of high radon exposure at higher risk of lung cancer>

READ: We now know exactly when the sugar tax is coming in>

Your Voice
Readers Comments
This is YOUR comments community. Stay civil, stay constructive, stay on topic. Please familiarise yourself with our comments policy here before taking part.
Leave a Comment
    Submit a report
    Please help us understand how this comment violates our community guidelines.
    Thank you for the feedback
    Your feedback has been sent to our team for review.

    Leave a commentcancel