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Dublin: 9 °C Thursday 23 May, 2013

Unborn babies could be tested for 3500 genetic conditions

Blood and saliva samples from parents could predict thousands of genetic conditions in unborn babies.

Image: Nogwater via Flickr/Creative Commons

US SCIENTISTS SAY unborn babies could be routinely tested for thousands of genetic conditions without disturbing either the mother or the foetus.

A team of scientists have been able to determine the genetic code of a foetus by taking a blood sample from a woman who was 18 weeks pregnant and a swab of saliva from the father.

The findings published in the journal Science Translational Medicine state that the test, which is non-invasive, will make it possible to scan for some 3500 disorders without physically disturbing either foetus or mother.

The new test can detect ‘de novo mutations’, which are not inherited, but are thought to play a role in complex conditions such as autism and schizophrenia.

Some conditions, such as Down’s syndrome, can already be detected prior to birth.

A spokesperson from the Pro-Life Campaign in Ireland told TheJournal.ie that there was a danger that the information from the new genetic test could be used to put the lives of many unborn babies at risk.

In January it was reported in the Irish Times that the Beacon Medical Group is to open a new clinic in Dublin that would offer pre-implantation genetic diagnosis. This is the first time a clinic has offered such a service in Ireland and could test embryos for conditions such as Huntington’s disease, haemophilia and cystic fibrosis.

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Comments (19 Comments)

  • Gattaca ! Movie comes to mind but if curable illnesses can be detected and
    Effects cured or minimised great!

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  • A bit embarrassing if the apparent father isn’t the actual father.

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  • Developments like this are a cause of concern if the intrinsic value and worth of every human being is not respected. We all have a right to be born and to contribute to society, regardless of our ability.
    Testing for conditions which cannot be cured is helpful insofar as it can allow families to prepare themselves to look after a baby with special needs. However, we must ensure that such a diagnosis is not used as a reason to advocate the ending of the unborn human life in question through abortion.

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    • And here comes the anti woman, misogynistic brigade yet again to tell women what they ought to do with themselves! Perhaps people like you Cora would do better to concern yourself with the rights of actual living children such as those receiving abuse at the hands of neglectful and monstrous adults than the perceived rights of a cluster of cells, yet to achieve a conscious state of being, to whom a woman can decide whether or not she wishes to give the potential of life to.

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    • Spot on Cora

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    • Man (or is he a mouse?) telling woman that she’s part of the “anti woman, misogynistic brigade.” Connor if you had brains you’d be dangerous.
      Connor tells Cora that she would do better to concern herself with thr rights of living children. Apart from the fact that he has no idea what Cora does the fact that a man would tell a woman what she should do is, err, misogynistic?
      Keep it up Connor!

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    • I am afraid Cora you can’t stop someone from taking the trip to the UK. I have little doubt that these tests will add to such travel. It is bordering on eugenics but I would not ban the technology.

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  • @Conor –

    There is nothing “anti woman” about what I have said – on the contrary. I am fully in favour of all types of scientific progress, once that progress recognises the fundamental right to life of every human life regardless of their age, status or ability.

    We already know that pre-natal testing can result in the abortion of many baby girls through the growing incidence of sex-selective abortions, a problem which is becoming more or prevalent even in so-called civilised societies like the UK. We must ensure that such discriminations do not get a foothold in this country.

    As for your comment regarding the rights of born children, of course I am in agreement that they must be protected but this is not at the expense of the unborn. I would be concerned at your comment regarding the ability of women tk “give life” to the unborn. As we know, basic biology teaches us that the unborn life is already alive and a member of the human race so there is no question if their being “given” rights by anyone. Those rights are inherent, it is only up to us to respect them.

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    • “We must ensure that such discriminations do not get a foothold in this country.” Wake up. They’re already here. And I love this idea that if you force a woman to have an unwanted daughter, the daughter will absolutely be treated wonderfully. Sex selective abortions are representative of the fact that in a lot of cultures, a son is valued more than a daughter. Maybe allowing women to control their reproductive systems might actually make a difference in that.

      “As we know, basic biology teaches us that the unborn life is already alive and a member of the human race so there is no question if their being “given” rights by anyone. Those rights are inherent, it is only up to us to respect them.” – That is your opinion. Biology has a hell of a lot of conflicting ideas as to what life is and what it means. Nature is actually the biggest abortion provider, so I have no idea where this idea that it’s “unnatural” comes from.

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    • And it’s anti woman for you to try to interfere in a private decision between myself, my partner and my doctor, thanks.

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    • @Nick -

      I share your disgust at the fact that in too many cultures, a son is valued more than a daughter. When this results in sex-selective abortion, it represents the most extreme form of gender discrimination and as such we should all work together to end its acceptance in any society.

      I can’t see how allowing women to control their reproductive systems would make a difference to this. Sex-selective abortions are based on a false recognition that men are more valuable to society than women – the way to attack such notions is to emphasise the inherent worth and dignity of every human life, regardless of gender. Control of reproductive systems is really something separate.

      My comment regarding biology is not an opinion – it’s based on basic embryology. A human life exists at conception. We may disregard the rights of that life through our laws or beliefs, but such laws cannot affect the fundamental fact that life exists.

      Is Nature the biggest abortion provider? Well, not if you think about what an abortion actually is – an action on the part of a human being to bring about the intentional end to the life of a separate unborn human being where the sole intention is to end that unborn life. We don’t have any control over what “Nature” does so the ending of unborn life in that way can only be a miscarriage, not an abortion. There is no element of “intention” involved.

      Finally, I would repeat that it is in no way “anti-woman” for me to advocate a position which seeks to defend the right to life of an unborn human life who may be at risk of having his/her life ended. An abortion is not the “private decision” that you would like it to be for the simple reason that a human life is at risk and is unable to defend himself/herself. In such cases, it is up to the rest of society to ensure that the life at risk is not arbitrarily ended.

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    • Well, not if you think about what an abortion actually is – an action on the part of a human being to bring about the intentional end to the life of a separate unborn human being where the sole intention is to end that unborn life. – Ah, you’re talking about a termination, rather than an abortion. An abortion includes both termination and miscarriage. Have you actually ready any embryonic textbooks? The purpose of a termination is to separate the foetus from the mother, rather than to specifically kill it.

      And I’m very sorry that you seem to believe that one of the basic tenets for women to achieve equality is not for women to be able to choose not to have children or to have more children than they’ feel able to deal with.

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    • JayK 08/06/12 #

      Nature is actually pretty specific about letting abnormal foetuses come to term. For example, approximately 80% of Down’s Syndrome conceptions are miscarried or “spontaneously aborted”.

      http://miscarriage.about.com/od/congenitaldisorders/qt/downsyndrome.htm

      As for “basic biology” defining life as beginning at conception, “life” itself is pretty loosely defined.

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  • So Nick says that allowing women have free access to abortion will ensure that less girl babies will be aborted … Wow, some jump. I wonder if he has any proof or if that came to him in a dream.
    Here’s the issue. We are talking about a human person here. If you believe that personhood gives rights, specifically the right to life then how can you say that under ANY circumstances abortion is good. If we are talking about a person they have rights regardless of their sex, the circumstances of their conception, whatever genetic “abnormality” (that itself is a horrible expression, it implies that anyone who is not genetically pure is somehow less than those who are, but I digress …). Whether an unborn person lives or dies is not a decision that anyone should have.
    If on the other hand the unborn is not a human person then you may have a point. So let me ask you do you think the unborn is a person, if not, why? When does a person become a person, when do they become human as it were (and thus start to have human rights, especially the right to life).

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    • I think a foetus is a person, actually. But I do not believe that a person ever has the right to live off of another human being without their consent. I believe at any time, a woman has the right to have a foetus removed from her body. In our society, we do not force parents to give an organ or a blood donation to a child who needs it desperately and I see this as no different.

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    • At least you’re honest. Abortion up until birth (and beyond, up until 18 years if you stretch the “live off of another person” definition).
      I wonder, is “live off of” the only criteria that you would apply to justify abortion on demand?

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    • Eleen 08/06/12 #

      Liam: the argument is about using another person’s body in order to stay alive, nothing else. They are not independent, they cannot survive without the woman’s body. There is no other instance when a person is legally compelled to use their body to keep another person alive. Why should it be different in this case? Especially when pregnancy is such a dangerous thing and alters a person’s body forever?

      That’s the crux of the matter – it doesn’t matter if you believe a fetus is a human baby or not. It’s just about whether you believe a living, breathing person has a right over their own body or not.

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  • “and beyond, up until 18 years if you stretch the “live off of another person” definition” – I believe a mother should be able to turn her child over to social services if she wishes (which is currently available). Her right does not extend to having it killed, but removing the dependency. So does that count?

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  • Nat Man 08/06/12 #

    This technology, I feel, will pave the way to giving each and every individual an equal footing in life.

    Reply

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