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Emergency talks look for ways to halt worst outbreak of Ebola in history

A suggestion that untested vaccines should be used has attracted controversy.

The Ebola virus.
The Ebola virus.
Image: theglobalpanorama via Flickr/Creative Commons

MINISTERS IN WEST Africa have held emergency talks on containing the worst Ebola outbreak in history, hoping to halt the virus’ deadly rampage after a jump in the number of deaths.

The highly-contagious tropical bug has infected hundreds of people in Guinea, Liberia and Sierra Leone, with the latest World Health Organization (WHO) figures showing that confirmed or suspected cases had left 467 people dead and experts fearing it could spread throughout the region.

Health ministers from 11 nations were due to finalise two days of talks in Accra with global experts in communicable diseases, with debate raging over the measures required to stop Ebola in its tracks.

Controversy

Jeremy Farrar, a professor of tropical medicine and director of The Wellcome Trust charity, caused controversy as the talks opened as he was widely quoted in global media calling on health authorities to offer experimental medicines, not yet fully tested, to patients.

“Tragic as these deaths and suffering are, humans are not Guinea pigs,” virologist Ian Mackay, associate professor at the University of Queensland, told AFP, rejecting the suggestion.

“It’s a very difficult situation made worse by the urgency of it.”

Potential vaccines

Several biotech companies and US universities are developing potential vaccines for Ebola, at various stages of testing, but none anywhere in the world is close to being licensed for distribution to the public.

“The question is: would these drugs be allowed to be used on UK citizens?” Mackay said.

If the outbreak occurred there, or in the US, or Australia, would this be ethically acceptable in these countries?

There are five species of Ebola, three of which — Zaire, Sudan and Bundibugyo — can kill humans.

Zaire Ebola, the deadliest and the species behind the current outbreak, can fell its victims within days, causing severe fever and muscle pain, weakness, vomiting and diarrhoea — in some cases shutting down organs and causing unstoppable bleeding.

There have been 21 Ebola outbreaks — not including isolated cases involving only one patient — since the virus first spread to humans in the Democratic Republic of Congo, then known as Zaire, in 1976.

1,587 people

Before the current crisis, Ebola had killed 1,587 people, two-thirds of those infected, according to an AFP tally based on WHO data.

The death rate for Ebola has been widely but incorrectly reported as “90 percent” by global media and some scientists, probably because around that percentage died in the original outbreak and a subsequent epidemic in neighbouring Congo-Brazzaville in 2003.

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The mortality rate in the west African epidemic is slightly lower than the average, at 61.5 percent, but it dwarves every other outbreak in terms of the geographical spread and the number of cases and deaths.

“Out of control”

Medical charity Doctors Without Borders, known by its French initials MSF, said last week the outbreak was “out of control”, with more than 60 hotspots.

However, experts say those who receive correct care — paracetamol to contain fevers, rehydration for diarrhoea and antibiotics for secondary infections — have a greatly improved chance of survival.

Ministers from Guinea, where 413 confirmed, suspected and probable cases have surfaced so far, including 303 deaths, and Liberia, which has seen 107 cases and 65 deaths, are at the Accra conference.

Sierra Leone, which has recorded 239 cases and 99 deaths, is also represented.

In addition, officials from Ivory Coast, Mali, Senegal, Gambia and Guinea-Bissau, along with Ghana and countries as far afield as Uganda and the Democratic Republic of Congo are attending.

- © AFP, 2014

Read: West Africa’s Ebola virus outbreak is now “out of control” >

More: DFA updates travel advice for Irish citizens, following Ebola outbreak >

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